Size-transformable antigen-presenting cell–mimicking nanovesicles potentiate effective cancer immunotherapy

Development of Artificial Antigen Presenting Cells for Prostate Cancer Immunotherapy

Nanoparticle-Based Manipulation of Antigen-Presenting Cells for Cancer Immunotherapy.

Immunotherapeutic approaches for treating cancer overall have been receiving a considerable amount of interest due to the recent approval of several clinical formulations. Among the different modalities, anticancer vaccination acts by training the body to endogenously generate a response against tumor cells. However, despite the large amount of work that has gone into the development of such va...

Cancer testis antigen and immunotherapy

The identification of cancer testis (CT) antigens has been an important advance in determining potential targets for cancer immunotherapy. Multiple previous studies have shown that CT antigen vaccines, using both peptides and dendritic cell vaccines, can elicit clinical and immunologic responses in several different tumors. This review details the expression of melanoma antigen family A, 1 (MAG...

Immunotherapy of Cancer

This article has no abstract.

Artificial antigen-presenting cells for use in adoptive immunotherapy.

The observation that T cells can recognize and specifically eliminate cancer cells has spurred interest in the development of efficient methods to generate large numbers of T cells with specificity for tumor antigens that can be harnessed for use in cancer therapy. Recent studies have demonstrated that during encounter with tumor antigen, the signals delivered to T cells by professional antigen...